Localizing unique and overlapping lesion locations in apraxia of speech and aphasia

Basilakos, Alexandra and Fridriksson, Julius and Fillmore, Paul and Yourganov, Grigori and Rorden, Chris (2014) Localizing unique and overlapping lesion locations in apraxia of speech and aphasia. [Clinical Aphasiology Paper]

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Abstract

Since Darley’s original description of apraxia of speech (AOS; 1968), controversy has centered around its diagnosis, treatment, and lesion location. Behaviors common to AOS are often shared among other communication disorders, complicating clinical management. The current study sought to identify crucial brain damage that causes apraxic speech, as well as errors common in both AOS and aphasia. Results revealed that damage to premotor and supplementary motor areas is unique to AOS, while involvement of temporal lobe areas predicts behaviors attributable to aphasia. These findings contribute to research regarding the neuroanatomical mechanism of AOS, and may ultimately improve differential diagnostic procedures.

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