Magnetoencephalographic evidence of neural plasticity following aphasia therapy

Faroqi-Shah, Yasmeen (2010) Magnetoencephalographic evidence of neural plasticity following aphasia therapy. [Clinical Aphasiology Paper]

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Abstract

This study used magnetoencephalography (MEG) to investigate changes in the spatio-temporal patterns of neural activity following language treatment in 6 individuals with chronic aphasia. All participants demonstrated agrammatic production profile with morphosyntactic deficits and responded positively to language treatment targeting verb morphology. MEG responses to an online morphological processing task were measure twice before initiation of treatment and once after cessation of treatment. All six participants demonstrated quantitative and qualitative changes in neural activity following aphasia therapy, and the spatiotemporal patterns were similar to those found in neurologically unimpaired participants. The results demonstrate that, in this study, neurophysiological changes following language therapy were specific to the linguistic process that was targeted, and not the result of general cognitive or compensatory mechanisms.

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