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Structure-function correspondences in Broca’s aphasia: Evidence from MRI and comprehension of verb phrase ellipsis constructions

Walenski, Matthew and Love, Tracy and Ferrill, Michelle and Deschamps, Isabelle and Pieperhoff, Peter and Amunts, Katrin and Grodzinsky, Yosef and Shapiro, Lewis P.
Structure-function correspondences in Broca’s aphasia: Evidence from MRI and comprehension of verb phrase ellipsis constructions. In Clinical Aphasiology Conference: Clinical Aphasiology Conference (2012 : 42nd : Lake Tahoe, CA : May 20-25, 2012) / : (2012).

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Abstract

We describe an effort to map lesion to behavior by studying the comprehension of complex VP-Ellipsis constructions (e.g., The policeman defended the child, and the dedicated fireman did___ too…) in participants with Broca‟s aphasia. We quantified the lesions of our individual participants using cytoarchitectonic probability maps of the human brain. We found that our Broca participants evinced delayed priming of the object in the ellipsis clause, while off-line comprehension was largely spared. Structure-function analyses revealed that lesions in both temporal and frontal areas participated in the behavioral outcomes, though each region seems to have played a distinct role.

EPrint Type:Clinical Aphasiology Paper
Subjects:UNSPECIFIED
ID Code:2421
Conference:Clinical Aphasiology Conference: Clinical Aphasiology Conference (2012 : 42nd : Lake Tahoe, CA : May 20-25, 2012)