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Relationships among the mismatch negativity (MMN) response, auditory comprehension, and site of lesion in aphasic adults

Auther, Linda L. and Wertz, Robert T. and Miller, Teya A. and Kirshner, Howard S.
Relationships among the mismatch negativity (MMN) response, auditory comprehension, and site of lesion in aphasic adults. Aphasiology, 14(5-6), 2000, pages 461-470.

Abstract

We evaluated the mismatch negativity (MMN) response to speech stimuli in aphasic adults to determine the relationships among aphasic patients' auditory comprehension, site of lesion, and the presence or absence of the MMN. Presence of a MMN response was significantly related to auditory comprehension performance. MMNs were present in 89% of the aphasic patients with good auditory comprehension and in 25% of the aphasic patients with poor auditory comprehension. Poor comprehension and the absence of a MMN were related to lesions in the temporal lobe. Good comprehension and the presence of a MMN response were related to lesions that spared the temporal lobe. However, the magnitude of these relationships was not perfect. Thus, the MMN as an index of auditory comprehension and its relationship to site of lesion may depend on where the lesion resides--primary auditory cortex and/or Wernicke's area--in the temporal lobe.

EPrint Type:Journal (Paginated)
Keywords:STIMULUS DEVIANCE; SPEECH; POTENTIALS
Subjects:UNSPECIFIED
ID Code:1161
Conference:Clinical Aphasiology Conference: Clinical Aphasiology Conference (1999 : 29th : Key West, FL : June 1999)
Conference Date:June 1999
Publisher:Taylor & Francis
Publication:Aphasiology
Volume:14
Number:5-6
Pages:461-470
Publication Location:London
ISSN:1464-5041
Alternative Locations:http://taylorandfrancis.metapress.com/openurl.asp?genre=article&issn=0268-7038&volume=14&issue=5&spage=461, http://taylorandfrancis.metapress.com/openurl.asp?genre=article&id=doi:10.1080/026870300401243
Additional Information:Access to Full Text is subject to the Publisher's access restrictions