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Wernicke's aphasia after putaminal hemorrhage: Unusual clinical and SPECT findings

Schneider, Sandra L and Wijdicks, F. M. and Duffy, Joseph R. and O'Brien, Terence J.
Wernicke's aphasia after putaminal hemorrhage: Unusual clinical and SPECT findings. Aphasiology, 13(9-11), 1999, pages 755-765.

Abstract

We present a case of a man with a putaminal hemorrhage who presented in the acute stage with a 'classic' Wernicke's aphasia. CT and MRI scans showed a large left basal ganglia hemorrhage involving the posterior putamen. A SPECT scan performed acutely demonstrated decreased perfusion in the left temporal cortex, frontal cortex and white matter and to the left basal ganglia from the hemorrhage itself. Within five days his language abilities improved dramatically, with complete resolution of his aphasia over the course of six weeks. Repeat SPECT scans continued to show the structural changes to the left putamen and left hemisphere hypoperfusion, suggesting that the resolution of the language symptoms did not correlate with the structural and perfusion changes. Various theories advanced in the literature regarding the pathophysiological mechanisms causing aphasia due to subcortical lesions cannot completely explain the findings of our case. These hypotheses are reviewed and discussed.

EPrint Type:Journal (Paginated)
Keywords:SUBCORTICAL APHASIA; BASAL GANGLIA; LESION SITES; LANGUAGE; RECOVERY; CT; IODOAMPHETAMINE; PROFILES
Subjects:UNSPECIFIED
ID Code:1150
Conference:Clinical Aphasiology Conference: Clinical Aphasiology Conference (1998 : 28th : Asheville, NC : June 1998)
Conference Date:June 1998
Publisher:Taylor & Francis
Publication:Aphasiology
Volume:13
Number:9-11
Pages:755-765
Publication Location:London
ISSN:1464-5041
Alternative Locations:http://taylorandfrancis.metapress.com/openurl.asp?genre=article&issn=0268-7038&volume=13&issue=9&spage=755, http://taylorandfrancis.metapress.com/openurl.asp?genre=article&id=doi:10.1080/026870399401858
Additional Information:Access to Full Text is subject to the Publisher's access restrictions