Patterns of language decline in non-fluent primary progressive aphasia
Thompson, C. K.. and Ballard, K. J. and Tait, M. E. and Weintraub, S. and Mesulam, M.
Patterns of language decline in non-fluent primary progressive aphasia. Aphasiology, 11(4-5), 1997, pages 297-321.
Language samples collected yearly for up to 11 years post-onset of symptoms from four subjects presenting with non-fluent primary progressive aphasia (PPA) were analyzed and compared with samples collected from both non-brain-damaged subjects and those with agrammatic Broca's aphasia resulting from a single left-hemisphere stroke. Extensive analysis of lexical and morphosyntactic variables in these samples revealed two patterns of expressive language decline in the PPA subjects - one resembling that seen in our agrammatic aphasic subjects - i.e. impaired production of closed-class elements and loss of sentential structures governed by these elements-and the other characterized by advancing word-retrieval difficulties. These data are relevant for patient-management purposes and, in addition, they provide information relevant to language representation and organization.
|EPrint Type:||Journal (Paginated)|
|Keywords:||GENERALIZED DEMENTIA; AGRAMMATIC PRODUCTION|
|Conference:||Clinical Aphasiology Conference: Clinical Aphasiology Conference (1996 : 26th : Newport, RI : June 1996)|
|Conference Date:||June 1996|
|Publisher:||Taylor & Francis|
|Additional Information:||Copyright by Taylor & Francis Ltd. Used with permission.|