Localizing lesion locations to predict extent of aphasia recovery

Thors, Helga and Fillmore, Paul and Rorden, Chris and Bonilha, Leonardo and Magnusdottir, Sigridur and Fridriksson, Julius (2014) Localizing lesion locations to predict extent of aphasia recovery. [Clinical Aphasiology Paper]

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Abstract

Extensive research has related specific lesion locations to language impairment in aphasia. However, far less work has focused on the patterns of brain damage that predict prognosis in aphasia. The current study examined brain damage as a predictor of language recovery in acute patients with aphasia caused by stroke. Damage to the left posterior middle temporal gyrus (MTG) and left pars triangularis predicted poor recovery of speech production and MTG damage predicted less recovery of speech comprehension. These findings suggest that brain changes associated with language recovery rely on preservation and recruitment of the aforementioned areas in the left hemisphere.

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