Neural Mechanisms of Verb Argument Structure Training in Agrammatic Aphasia

Den Ouden, Dirk-Bart and Riley, Ellyn and Lukic, Sladjana and Thompson, Cynthia (2010) Neural Mechanisms of Verb Argument Structure Training in Agrammatic Aphasia. [Clinical Aphasiology Paper]

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Abstract

In four speakers with agrammatic aphasia, we examined the effects of training verbs with complex argument structure in sentence contexts, behaviorally and with respect to the neural mechanisms of recovery. It was hypothesized that training ditransitive verbs would result in generalization to less-complex verb types (transitive and intransitive) in both verb naming and sentence production and that these behavioral changes would be associated with observable shifts in fMRI brain activation patterns from pre- to post-treatment. Results showed different behavioral and neural activation patterns of pre-post change across participants, which will be discussed

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